Volume 19, No. 4, 2022
Efficacy Of Autologous Platelet Rich Fibrin In Myringoplasty In Dogs
Samy M. El-Sayed , Nagy M. Iskander , Diaa ElDin M. ElHennawi , Yasser T. Madian ; and Alaa M. Farid
Abstract
Objectives: To assess the effect of local application of platelet rich fibrin in myringoplasty for perforated dogs’ tympanic membranes. Material and methods: forty four dogs were subjected to large central tympanic perforation (at least two quadrant) in right ears and Follow up for 8 weeks and further were divided into two equal groups randomly by lottery. Group (A): study group: PRF was been used in repairing dry chronic tympanic perforation in dogs in their right ears. Group (B): control group: PRF was not been used only trimming of the edges of tympanic membrane perforation. Closure of perforated tympanic membrane with platelet-rich fibrin membrane was assessed by healing. Results: Percentage of healing of study group was 47.5% versus 25% among control group. There were statistically significant difference between Study Group and Control Group regarding Healing at 8 weeks. Percentage of healing of study group was 90% versus 75% among control group. Conclusion: PRF membrane could be used successfully in the repair of tympanic membrane perforation and wound healing. This method could be more frequently preferred in the future in various areas as it is an autogenous material which is safe and effective, easy to use, and has low costs, while it does not prolong operating time.
Pages: 505-511
Keywords: Myringoplasty, perforated tympanic membrane, PRF.